REVIEW Anaphylaxis: mechanisms and management J. K. Lee and P. Vadas, Clinical & Experimental Allergy, 2011 (41) 923–938.                           Anaphylaxis is a serious allergic reaction that can be rapid in onset and occasionally fatal. This is a review of the literature on the epidemiology of anaphylaxis, diagnostic criteria, mechanisms, and management. This current review of the literature is intended for clinicians, trainees, and researchers as a comprehensive review of anaphylaxis with a focus on incorporating the latest advances in the field.